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But because of the lack of regulations, the way its consumed, and the risk of contaminants and adulterants people can become dependent or addicted. K2, spice, and skunk: off-the-charts intoxicating Unlike delta-8, synthetic cannabinoids are a class of substances that are made in a lab and designed to mimic THC from cannabis

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In many situations, it is the safest option, the most affordable, often the most environmentally reasonable, and sometimes simply impossible to replace without losing effectiveness or creating new risks